Pharmaceutical Grade Phentolamine Powder CAS 50-60-2

Hot Selling Pharmaceutical Grade Phentolamine Powder with Best Price CAS 50-60-2

• Product description

• Product name	Phentolamine
  CAS No.	50-60-2
  Molecular Formula	C17H19N3O
  Molecular weight	281.35
  Grade Standard	Medicine Grade
  COA	Avaliable

Product intoduction:

Phentolamine is used in the diagnosis of vasospasm diseases, such as acral arterial spasm (i.e. Raynaud's disease), cyanosis of hands and feet, septic toxic shock and pheochromocytoma. It is also effective for ventricular premature beats.

Product Function:

Phentolamine is competitive and non selective α 1 and α 2 receptor blocker, its action duration is short. By blocking the cell process junction α 1 and α 2 receptor, which causes vasodilation and reduction of blood pressure, mainly arterioles, followed by veins. As a result, the resistance of systemic circulation and pulmonary circulation and arterial pressure are reduced; Through block α 2 receptor, which can increase the release of noradrenaline from the upper gland, resulting in increased myocardial contractility and tachycardia. Phentolamine also reduced renal perfusion pressure and caused * retention of sodium. It can also antagonize the vasoconstrictive response induced by noradrenaline and a drenaline. Due to the pre junction of cell process α The blocking effect of 1 receptor leads to the increase of the release of noradrenergic hormone from neurons. Phentolamine can enhance the contractility and rate of myocardium. After intravenous administration, the systemic mean arterial pressure and systemic vascular resistance can be temporarily reduced.

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