CAS 51-05-8 Procaine HCl Local Anesthetic Drugs , Procaine Hydrochloride

CAS 51-05-8 Procaine HCl Local Anesthetic Drugs , Procaine Hydrochloride

Description
Procaine HCl (procaine hydrochloride) is the active ingredient in Gerovital H3(GH3) and in the Vitacels 3 through 8. Procaine HCl is broken down rapidly by enzymes in the blood stream into PABA and DEAE. The PABA and DEAE are rapidly conjugated and removed from the blood and excreted from the body. Because of this procaine HCl and its breakdown products (metabolites) are unable to get into the cells in any great quantity to produce benefits. Procaine HCl will produce some benefits by itself, but they are very limited.
However when procaine HCl is complexed properly (Koch process)(1) the procaine HCl is protected from the action of the enzymes in the blood and tissues this protection gives the procaine enough time to be transfered into the cells of the body where it helps the cells rebuild, repair, and detoxify. This action of the procaine HCl complex is responsible for the remarkable improvements in health that result from the use of GH3 and the Vitacel 3 - 8.


Specification
Product name: Procaine HCl
Alias: Procaine hydrochloride;aminocaine;anadolor;atoxicocaine;
CAS register number:51-05-8
Assay: 99.5%
EINECS : 200-077-2
Molecular formula: C13H21ClN2O2
Molecular weight: 272.77
Molecular structure:



Grade : Pharmaceutical Grade
Storage: Shading, confined preservation
Appearance: White crystalline powder
Delivery: EMS, DHL, TNT, FedEx, UPS
Usage : Procaine hydrochloride is a kind of local anesthetics, for local anesthesia, nerve block etc, can block the conduction of nerve fibers with anesthetic effect, strong function, low toxicity, and no addiction, but the skin, mucous membrane penetration force is weak, not suitable for surface anesthesia, clinically used to infiltration, spine and conduction anesthesia.

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COA

Application
Procaine HCl is a local anesthetic drug of the amino ester group. It is used primarily to reduce the pain of intramuscular injection of penicillin, and it is also used in dentistry. Owing to the ubiquity of the trade name Novocain, in some regions procaine is referred to generically as novocaine. It acts mainly by being a sodium channel blocker.Today it is used therapeutically in some countries due to its sympatholytic, anti-inflammatory, perfusion enhancing, and mood enhancing effects.

Procaine HCl is indicated for the production of local or regional analgesia and anesthesia by local infiltration and peripheral nerve block techniques.

Application of procaine leads to the depression of neuronal activity. The depression causes the nervous system to become hypersensitive producing restlessness and shaking, leading to minor to severe convulsions. Studies on animals have shown the use of procaine led to the increase of dopamine and serotonin levels in the brain.Other issues may occur because of varying individual tolerance to procaine dosage. Nervousness and dizziness can arise from the excitation of the central nervous system, which may lead to respiratory failure if overdosed. Procaine may also induce weakening of the myocardium leading to cardiac arrest.


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