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Fever Reducer Local Anesthetic Drugs Paracetamol / 4-Acetamidophenol Powder 103-90-2

Wuhan Senwayer Century Chemical Co.,Ltd

Fever Reducer Local Anesthetic Drugs Paracetamol / 4-Acetamidophenol Powder 103-90-2

Brand Name : Senwayer

Model Number : 103-90-2

Certification : GMP,ISO9001,KOSHER

Place of Origin : China

Payment Terms : T/T, , MoneyGram,,Bitcoin

Supply Ability : Mass stock

Delivery Time : 3-5 working days

Packaging Details : Discreet disguised package or as required

MOQ : Negotiation

Price : Negotiation

CAS Number : 103-90-2

MF : C8H9NO2

MW : 151.1649

EINECS Number : 203-157-5

Melting point : 168-172 ºC

Appearance : White crystalline powder

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Fever Reducer Local Anesthetic Drugs Paracetamol / 4-Acetamidophenol Powder 103-90-2


Description:


Paracetamol is a commonly used medicine that can help treat pain and reduce a high temperature (fever). It's typically used to relieve mild or moderate pain, such as headaches, toothache or sprains, and reduce fevers caused by illnesses such as colds and flu.


Paracetamol is often recommended as one of the first treatments for pain, as it's safe for most people to take and side effects are rare.


Specifications:


English name: 4-Acetamidophenol
Synonyms: Acetaminophen; 4-Hydroxyacetanilide; Paracetamol; APAP; p-Hydroxyacetanilide; 4-Acetamino phenol; Acetaminphen; Paracetamol DC; N-Acetyl-4-aminophenol; N- (4-hydroxyphenyl) acetamide; Acetamiophen
CAS: 103-90-2
EINECS Number: 203-157-5
Formula: C8H9NO2
MW: 151.1649
Water-soluble: 14 g / L (20 ºC)
Melting point: 168-172 ° C
Water-soluble: 14 g / L (20 ° C)
Uses:Anti-inflammatory drugs
Assay: 99%
Appearance: White crystalline powder


2D Structure:



COA:


TestsStandardsResults
AppearanceWhite or almost white ,crystalline powder.White,crystalline powder.
IdentificationA:IR absorptionCompliesComplies
B:UV absorptionCompliesComplies
C:TLCCompliesComplies
Melting point168~172C169.0~170.9C
WaterNot more than0.5%0.08%
Related substanceImpurity(chloroacetanilide)not more than 10 ppm2ppm
Impurity K(4-aminophenol)not more than 50 ppm15 ppm
Impurity F(4-nitrophenol)not more than 0.05%Not detected
any other impurity not more than 0.05%0.01%
Total of other impurities not more than 0.1%0.02%
Residue on ignitionNot more than 0.1%0.05%
ChlorideNot more than 0.014%Less than 0.014%
SulfateNot more than 0.02%Less than 0.02%
SulfideConformsConforms
Heavy metalsNot more than 0.001%Less than 0.001%
Free p-aminophenolNot more than 0.005%Less than 0.005%
Limit of Pchloroa
cetanilide
Not more than 0.001%Less than 0.001%
Readily carbonizable substancesConformsConforms
Residual solventsResidual content of acetic acid is limited by the test of loss on dryingnot more than0.5%0.08%
Assay(anhydrous basis)99.0~101.0%99.6%
Conclusion: Complies with USP34 / BP2011

Applications:


1. Medical uses:


Fever
Paracetamol is used for reducing fever in people of all ages. The World Health Organization (WHO) recommends that paracetamol be used to treat fever in children only if their temperature is greater than 38.5 °C (101.3 °F).[24] The efficacy of paracetamol by itself in children with fevers has been questioned and a meta-analysis showed that it is less effective than ibuprofen.


Pain
Paracetamol is used for the relief of mild to moderate pain. The use of the intravenous form for pain of sudden onset in people in the emergency department is supported by limited evidence.


Osteoarthritis
The American College of Rheumatology recommends paracetamol as one of several treatment options for people with arthritis pain of the hip, hand, or knee that does not improve with exercise and weight loss.A 2015 review, however, found it provided only a small benefit in osteoarthritis.


Paracetamol has relatively little anti-inflammatory activity, unlike other common analgesics such as the NSAIDs aspirin and ibuprofen, but ibuprofen and paracetamol have similar effects in the treatment of headache. Paracetamol can relieve pain in mild arthritis, but has no effect on the underlying inflammation, redness, and swelling of the joint.It has analgesic properties comparable to those of aspirin, while its anti-inflammatory effects are weaker. It is better tolerated than aspirin due to concerns about bleeding with aspirin.


Low back pain
Based on a systematic review, paracetamol is recommended by the American College of Physicians and the American Pain Society as a first-line treatment for low back pain.However, other systematic reviews concluded that evidence for its efficacy is lacking.


Headaches
A joint statement of the German, Austrian, and Swiss headache societies and the German Society of Neurology recommends the use of paracetamol in combination with caffeine as one of several first line therapies for treatment of tension or migraine headache.In the treatment of acute migraine, it is superior to placebo, with 39% of people experiencing pain relief at 1 hour compared to 20% in the control group.


Postoperative pain
Paracetamol combined with NSAIDs may be more effective for treating postoperative pain than either paracetamol alone or NSAIDs alone.


Other
The efficacy of paracetamol when used in combination with weak opioids (such as codeine) improved for approximately 50% of people but with increases in the number experiencing side effects.Combination drugs of paracetamol and strong opioids like morphine improve analgesic effect.

The combination of paracetamol with caffeine is superior to paracetamol alone for the treatment of common pain conditions including dental pain, postpartum pain, and headache.


2. Veterinary use:


Paracetamol has also been widely used in the veterinary area, the effect has been proved by the treatment of cats, dogs, snakes, and other animals without or with rare side effects.


How to Take Paracetamol?


How much you can take depends on your age, your weight, the type of paracetamol you're taking and how strong it is. For example:
Adults can usually take one or two 500mg tablets every 4-6 hours, but shouldn't take more than 4g (eight 500mg tablets) in the space of 24 hours.


Children under 16 need to take a lower dose, depending on their age or weight - check the packet or leaflet, or ask a pharmacist or doctor for advice. For very young children, paracetamol liquid is given using a measuring spoon or an oral syringe.


Paracetamol should start to work within an hour and the effect usually lasts several hours. Don't take more than the recommended dose if it isn't relieving your symptoms.


Adults can take ibuprofen at the same time if necessary, but this isn't usually recommended for children.



Paracetamol Storage:


A: Keep out of the reach and sight of children.
B: Store below 25° C in a dry place, protected from light.
C: Do not use Paracetamol tablets after the expiry date stated on the label/carton/bottle. The expiry date refers to the last day of that month.


Packaging & Delivery:

1. Sufficient stock.
2. Sophisticated and professional logistic agent.
3. Well-trained and disciplined packing team. Unique ways to ship 10 grams to 100kg powders at one time to your destination. Fast and discreet shipment could be arranged for customs pass Guaranteed.
4. Packing pictures and tacking code are provided within 12 hours after receiving the payment.
5. After-sale service: Any questions or problems after receiving the product, please feel free to contact us. Problems would be solved immediately.



If you have any question pls feel free to contact me via:

Email: export@senwayer.com
Whats-app:+86-18186442580
Wickr me:yukis8888
We-chat:+86-18186442580
Tele-gram:+86-18186442580


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